MESP2 (mesoderm posterior BHLH transcription factor 2) is a protein coding gene.
Diseases associated with MESP2 include spondylocostal dysostosis 2, autosomal recessive and spondylocostal dysostosis, autosomal recessive.
Among its related pathways are cardiac progenitor differentiation and gene regulatory network modelling somitogenesis.
MESP2 encodes a member of the bHLH family of transcription factors and plays a key role in defining the rostrocaudal patterning of somites via interactions with multiple notch signaling pathways.
MESP2 is expressed in the anterior presomitic mesoderm and is downregulated immediately after the formation of segmented somites.
MESP2 also plays a role in the formation of epithelial somitic mesoderm and cardiac mesoderm.
Mutations in the MESP2 gene cause autosomal recessive spondylocostal dystosis 2 (SCD02).
Applications:Suitable for use in Western Blot and ELISA.
Other applications not tested.
Recommended Dilution:Western Blot: 1:500-1:2000ELISA: 1:5000-1:20,000Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：30ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid in PBS, pH 7.4, 0.02% sodium azide, 50% glycerol.
Specificity：Recognizes endogenous levels of human MESP2.
Isotype：IgG
Calc Applications Abbrev：E WB
Calc Crossreactivity：Hu
Immunogen：Synthetic peptide corresponding to aa220-300 from human MESP2.
