84-5514-79　［取扱停止］MDR3 30ul　538846

特徴

• ABCB4 (ATP binding cassette subfamily B member 4) is a protein coding gene.
• Diseases associated with ABCB4 include cholestasis, progressive familial intrahepatic 3 and gallbladder disease 1.
• Among its related pathways are nuclear receptors in lipid metabolism and toxicity and hepatic ABC transporters.
• The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters.
• ABC proteins transport various molecules across extra and intra-cellular membranes.
• ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White).
• This protein is a member of the MDR/TAP subfamily.
• Members of the MDR/TAP subfamily are involved in multidrug resistance as well as antigen presentation.
• This gene encodes a full transporter and member of the p-glycoprotein family of membrane proteins with phosphatidylcholine as its substrate.
• Applications:Suitable for use in Western Blot and ELISA.
• Other applications not tested.
• Recommended Dilution:Western Blot: 1:500-1:2000ELISA: 1:5000-1:20,000Optimal dilutions to be determined by the researcher.
• Storage and Stability:May be stored at 4°C for short-term only.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Aliquots are stable for 12 months after receipt.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.