MAF1 (MAF1 homolog, negative regulator of RNA polymerase III) encodes a protein that is similar to Maf1, a Saccharomyces cerevisiae protein highly conserved in eukaryotic cells.
Yeast Maf1 is a negative effector of RNA polymerase III (Pol III).
It responds to changes in the cellular environment and represses pol III transcription.
Biochemical studies identified the initiation factor TFIIIB as a target for Maf1-dependent repression.
Applications:Suitable for use in Immunohistochemistry, ELISA.
Other applications not tested.
Recommended Dilution:Immunohistochemistry (paraffin): 1:100-1:300ELISA: 1:20,000Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size:100ul
Host:rabbit
Source Antibody:human
Grade:Affinity Purified
Purity:Purified by immunoaffinity chromatography.
Form:Supplied as a liquid in PBS, 0.5% BSA, 0.02% sodium azide, 50% glycerol.
Specificity:Recognizes endogenous levels of human Maf1. Species Crossreactivity: Mouse, rat
Isotype:IgG
Calc Applications Abbrev:E IHC
Calc Crossreactivity:Hu Mo Rt
Immunogen:Synthetic peptide corresponding to a110-190 from the Internal region of human Maf1.