The protein encoded by TNFSF14 (tumor necrosis factor superfamily member 14) is a member of the tumor necrosis factor (TNF) ligand family.
This protein is a ligand for TNFRSF14, which is a member of the tumor necrosis factor receptor superfamily, and which is also known as a herpesvirus entry mediator (HVEM).
This protein may function as a costimulatory factor for the activation of lymphoid cells and as a deterrent to infection by herpesvirus.
This protein has been shown to stimulate the proliferation of T cells, and trigger apoptosis of various tumor cells.
This protein is also reported to prevent tumor necrosis factor alpha mediated apoptosis in primary hepatocyte.
Two alternatively spliced transcript variant encoding distinct isoforms have been reported.
Applications:Suitable for use in Immunofluorescence and ELISA.
Other applications not tested.
Recommended Dilution:Immunofluorescence: 1:200-1:1000ELISA: 1:20,000Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：30ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid in PBS, 0.5% BSA, 0.02% sodium azide, 50% glycerol.
Specificity：Recognizes endogenous levels of human LIGHT. Species Crossreactivity: mouse
Isotype：IgG
Calc Applications Abbrev：E IF
Calc Crossreactivity：Hu Mo
Immunogen：Synthetic peptide corresponding to aa30-110 from the Internal region of human LIGHT.
