84-5505-91　［取扱停止］Kv1.3 100ul　538379

特徴

• Potassium channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints.
• Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume.
• Four sequence-related potassium channel genes - shaker, shaw, shab, and shal - have been identified in Drosophila, and each has been shown to have human homolog(s).
• KCNA3 encodes a member of the potassium channel, voltage-gated, shaker-related subfamily.
• Potassium voltage-gated channel subfamily A member 3 contains six membrane-spanning domains with a shaker-type repeat in the fourth segment.
• It belongs to the delayed rectifier class, members of which allow nerve cells to efficiently repolarize following an action potential.
• It plays an essential role in T-cell proliferation and activation.
• This gene appears to be intronless and it is clustered together with KCNA2 and KCNA10 genes on chromosome 1.
• Applications:Suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence, and ELISA.
• Other applications not tested.
• Recommended Dilution:Western Blot: 1:500-1:2000Immunohistochemistry (paraffin): 1:100-1:300Immunofluorescence: 1:200-1:1000ELISA: 1:20,000Optimal dilutions to be determined by the researcher.
• Storage and Stability:May be stored at 4°C for short-term only.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Aliquots are stable for 12 months after receipt.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.