Zinc Finger Protein 24 is a transcription factor required for myelination of differentiated oligodendrocytes.
Required for the conversion of oligodendrocytes from the premyelinating to the myelinating state.
In the developing central nervous system (CNS), involved in the maintenance in the progenitor stage by promoting the cell cycle.
Specifically binds to the 5-TCAT-3 DNA sequence (By similarity).
Has transcription repressor activity in vitro.
Gene Ontology (GO) annotations related to this gene include transcription factor activity, sequence-specific DNA binding and sequence-specific DNA binding.
An important paralog of this gene is ZSCAN16.
Applications:Suitable for use in Western Blot, Immunohistochemistry, and ELISA.
Other applications not tested.
Recommended Dilution:Western Blot: 1:500-1:2000Immunohistochemistry (paraffin): 1:100-1:300ELISA: 1:10,000Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size:30ul
Host:rabbit
Source Antibody:human
Grade:Affinity Purified
Purity:Purified by immunoaffinity chromatography.
Form:Supplied as a liquid in PBS, 0.5% BSA, 0.02% sodium azide, 50% glycerol.
Specificity:Recognizes endogenous levels of human KOX17. Species Crossreactivity: mouse and rat
Isotype:IgG
Calc Applications Abbrev:E IHC WB
Calc Crossreactivity:Hu Mo Rt
Immunogen:Synthetic peptide corresponding to aa10-90 of human KOX17 at N-terminal.