KCNJ10 (potassium voltage-gated channel subfamily J member 10) encodes a member of the inward rectifier-type potassium channel family, characterized by having a greater tendency to allow potassium to flow into, rather than out of, a cell.
The encoded protein may form a heterodimer with another potassium channel protein and may be responsible for the potassium buffering action of glial cells in the brain.
Mutations in KCNJ10 have been associated with seizure susceptibility of common idiopathic generalized epilepsy syndromes.
Applications:Suitable for use in Immunohistochemistry.
Other applications not tested.
Recommended Dilution:Immunohistochemistry (paraffin): 1:100-1:200Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size:100ul
Host:rabbit
Grade:Affinity Purified
Purity:Purified by immunoaffinity chromatography.
Form:Supplied as a liquid in PBS, 0.5% BSA, 0.02% sodium azide, 50% glycerol.
Specificity:Recognizes Kir4.1. Species Crossreactivity: human, mouse and rat
Isotype:IgG
Calc Applications Abbrev:IHC
Calc Crossreactivity:Hu Mo Rt
Immunogen:Synthetic peptide corresponding to Kir4.1.