KDM3B (lysine demethylase 3B) is a protein coding gene.
Diseases associated with KDM3B include persistent hyperplastic primary vitreous.
Among its related pathways are chromatin organization and activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3.
Histone demethylase that specifically demethylates Lys-9 of histone H3, thereby playing a central role in histone code.
Demethylation of Lys residue generates formaldehyde and succinate.
May have tumor suppressor activity.
Applications:Suitable for use in Western Blot and ELISA.
Other applications not tested.
Recommended Dilution:Western Blot: 1:500-1:2000ELISA: 1:5000-1:20,000Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size:100ul
Host:rabbit
Source Antibody:human
Grade:Affinity Purified
Purity:Purified by immunoaffinity chromatography.
Form:Supplied as a liquid in PBS, pH 7.4, 0.02% sodium azide, 50% glycerol.
Specificity:Recognizes endogenous levels of human KDM3B. Species Crossreactivity: mouse
Isotype:IgG
Calc Applications Abbrev:E WB
Calc Crossreactivity:Hu Mo
Immunogen:Synthetic peptide corresponding to aa230-310 from the internal region of human KDM3B.