KCNQ5 (potassium voltage-gated channel subfamily Q member 5) is a member of the KCNQ potassium channel gene family that is differentially expressed in subregions of the brain and in skeletal muscle.
The protein encoded by KCNQ5 yields currents that activate slowly with depolarization and can form heteromeric channels with the protein encoded by the KCNQ3 gene.
Currents expressed from this protein have voltage dependences and inhibitor sensitivities in common with M-currents.
They are also inhibited by M1 muscarinic receptor activation.
Multiple transcript variants encoding different isoforms have been found for KCNQ5.
Applications:Suitable for use in Western Blot and ELISA.
Other applications not tested.
Recommended Dilution:Western Blot: 1:500-1:2000ELISA: 1:40,000Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：100ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid in PBS, 0.5% BSA, 0.02% sodium azide, 50% glycerol.
Specificity：Recognizes endogenous levels of human KCNQ5. Species Crossreactivity: mouse
Isotype：IgG
Calc Applications Abbrev：E WB
Calc Crossreactivity：Hu Mo
Immunogen：Synthetic peptide corresponding to aa610-690 from human KCNQ5.
