84-5501-83　［取扱停止］JNK3 100ul　538173

特徴

• The protein encoded by MAPK10 (mitogen-activated protein kinase 10) is a member of the MAP kinase family.
• MAP kinases act as integration points for multiple biochemical signals and are involved in a wide variety of cellular processes, such as proliferation, differentiation, transcription regulation and development.
• This kinase is specifically expressed in a subset of neurons in the nervous system and is activated by threonine and tyrosine phosphorylation.
• Targeted deletion of this gene in mice suggests that it may have a role in stress-induced neuronal apoptosis.
• Alternatively spliced transcript variants encoding different isoforms have been described for MAPK10.
• A recent study provided evidence for translational readthrough in MAPK10 and expression of an additional C-terminally extended isoform via the use of an alternative in-frame translation termination codon.
• Applications:Suitable for use in Immunohistochemistry.
• Other applications not tested.
• Recommended Dilution:Immunohistochemistry (paraffin): 1:50-1:200Optimal dilutions to be determined by the researcher.
• Storage and Stability:May be stored at 4°C for short-term only.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Aliquots are stable for 12 months after receipt.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.