SPAG9 (sperm associated antigen 9) encodes a member of the cancer testis antigen gene family.
The encoded protein functions as a scaffold protein that structurally organizes mitogen-activated protein kinases and mediates c-Jun-terminal kinase signaling.
This protein also binds to kinesin-1 and may be involved in microtubule-based membrane transport.
This protein may play a role in tumor growth and development.
Alternate splicing results in multiple transcript variants.
SPAG9 is a protein coding gene.
Diseases associated with SPAG9 include cardiomyopathy, hypertrophic, 2 and Hodgkin's Lymphoma, Mixed cellularity.
Among its related pathways are Arf6 trafficking events and Akt Signaling.
Applications:Suitable for use in Western Blot and ELISA.
Other applications not tested.
Recommended Dilution:Western Blot: 1:500-1:2000ELISA: 1:5000-1:20,000Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：30ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid in PBS, pH 7.4, 0.02% sodium azide, 50% glycerol.
Specificity：Recognizes endogenous levels of human JIP4. Species Crossreactivity: mouse
Isotype：IgG
Calc Applications Abbrev：E WB
Calc Crossreactivity：Hu Mo
Immunogen：Synthetic peptide corresponding to aa590-670 from the internal region of human JIP4.
