DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases.
The protein encoded by this gene is a DEAD box protein that is part of a complex that interacts with the C-terminal of RNA polymerase II and is involved in 3' end processing of snRNAs.
In addition, this gene is a candidate tumor suppressor and is located in the critical region of loss of heterozygosity (LOH).
Multiple transcript variants encoding different isoforms have been found for this gene.
INT6 (Integrator Complex Subunit 6) is a protein coding gene.
Among its related pathways are RNA polymerase II transcribes snRNA genes and gene expression.
Applications:Suitable for use in Western Blot and ELISA.
Other applications not tested.
Recommended Dilution:Western Blot: 1:500-1:2000ELISA: 1:5000-1:20,000Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：100ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid in PBS, pH 7.4, 0.02% sodium azide, 50% glycerol.
Specificity：Recognizes endogenous levels of human INT6. Species Crossreactivity: mouse
Isotype：IgG
Calc Applications Abbrev：E WB
Calc Crossreactivity：Hu Mo
Immunogen：Synthetic peptide corresponding to aa550-630 from the internal region of human INT6.
