The protein encoded by IL17RB (interleukin 17 receptor B) is a cytokine receptor.
This receptor specifically binds to IL17B and IL17E, but does not bind to IL17 and IL17C.
This receptor has been shown to mediate the activation of NF-kappaB and the production of IL8 induced by IL17E.
The expression of the rat counterpart of IL17RB was found to be significantly up-regulated during intestinal inflammation, which suggested the immunoregulatory activity of this receptor.
Applications:Suitable for use in Western Blot and ELISA.
Other applications not tested.
Recommended Dilution:Western Blot: 1:500-1:2000ELISA: 1:10,000-1:20,000Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：30ul
Host：rabbit
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid in PBS, 0.5% BSA, 0.02% sodium azide, 50% glycerol.
Specificity：Recognizes endogenous levels of IL-17RB. Species Crossreactivity: human
Isotype：IgG
Calc Applications Abbrev：E WB
Calc Crossreactivity：Hu
Immunogen：Synthetic peptide corresponding to aa251-300 from IL-17RB.
