HOXB3 is a member of the antp homeobox family and encodes a nuclear protein with a homeobox DNA-binding domain.
It is included in a cluster of homeobox B genes located on chromosome 17.
The encoded protein functions as a sequence-specific transcription factor that is involved in development.
Increased expression of HOXB3 is associated with a distinct biologic subset of acute myeloid leukemia (AML).
HOXB3 (homeobox B3) is a protein coding gene.
Among its related pathways are activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3 and developmental biology.
Applications:Suitable for use in Western Blot and ELISA.
Other applications not tested.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：100ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid in PBS, pH 7.4, 0.02% sodium azide, 50% glycerol.
Specificity：Recognizes endogenous levels of human HXB3. Species Crossreactivity: mouse
Isotype：IgG
Calc Applications Abbrev：E WB
Calc Crossreactivity：Hu Mo
Immunogen：Synthetic peptide corresponding to human HXB3 protein.
