HSPA8 (heat shock protein family A (Hsp70) member 8) encodes a member of the heat shock protein 70 family, which contains both heat-inducible and constitutively expressed members.
This protein belongs to the latter group, which are also referred to as heat-shock cognate proteins.
It functions as a chaperone, and binds to nascent polypeptides to facilitate correct folding.
It also functions as an ATPase in the disassembly of clathrin-coated vesicles during transport of membrane components through the cell.
Alternatively spliced transcript variants encoding different isoforms have been found for HSPA8.
Applications:Suitable for use in Western Blot and Immunohistochemistry.
Other applications not tested.
Recommended Dilution:Western Blot: 1:500-1:2000Immunohistochemistry (paraffin): 1:50-1:2000Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：100ul
Host：rabbit
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid in PBS, pH 7.4, 0.02% sodium azide, 50% glycerol.
Specificity：Recognizes endogenous HSC70. Species Crossreactivity: human, mouse and rat
Isotype：IgG
Calc Applications Abbrev：IHC WB
Calc Crossreactivity：Hu Mo Rt
Immunogen：Recombinant protein corresponding to heat shock cognate 71kD. (heat shock 70kD protein 8)
