The high mobility group nucleosome binding domain 1 encoded by HMGN1 binds nucleosomal DNA and is associated with transcriptionally active chromatin.
Along with a similar protein, HMG17, the encoded protein may help maintain an open chromatin configuration around transcribable genes.
Applications:Suitable for use in Immunohistochemistry, Immunofluorescence, and ELISA.
Other applications not tested.
Recommended Dilution:Immunohistochemistry (paraffin): 1:100-1:300Immunofluorescence: 1:200-1:1000ELISA: 1:10,000Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size:30ul
Host:rabbit
Source Antibody:human
Grade:Affinity Purified
Purity:Purified by immunoaffinity chromatography.
Form:Supplied as a liquid in PBS, 0.5% BSA, 0.02% sodium azide, 50% glycerol.
Specificity:Recognizes endogenous levels of human HMG-14 (phospho Ser21). Species Crossreactivity: mouse and rat
Isotype:IgG
Calc Applications Abbrev:E IF IHC
Calc Crossreactivity:Hu Mo Rt
Immunogen:Synthetic peptide corresponding to human HMG-14 around the phosphorylation site of S21.