Human major histocompatibility complex (MHC) antigens, also referred to as human leukocyte antigens (HLA), are encoded by genes located on the short arm of chromosome 6.
There are two classes of HLA antigens: class I (HLA-A, B and C) and class II (HLA-D).
This class I molecules are polymorphic membrane glycoproteins composed of a heavy (alpha) chain (44kD) which is encoded by a HLA class I gene (HLA-A, B or C), and beta2-microglobulin light (beta) chain (12kD).
They are involved in the presentation of foreign antigens to the immune system.
(PMID: 667938; 3375250)
Applications:Suitable for use in Western Blot and ELISA.
Other applications not tested.
Recommended Dilution:Western Blot: 1:500-1:10,000ELISA: 1:10,000Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：100ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid in PBS, pH 7.4, 0.02% sodium azide, 50% glycerol.
Specificity：Recognizes endogenous HLA Class I.
Isotype：IgG
Calc Applications Abbrev：E WB
Calc Crossreactivity：Hu
Immunogen：Synthetic peptide corresponding to aa220-270 of human HLA Class I.
