84-5483-45 ［取扱停止］HES5 30ul 537176
特徴
- HES5 (hes family BHLH transcription factor 5) encodes a member of a family of basic helix-loop-helix transcriptional repressors.
- The protein product of HES5, which is activated downstream of the notch pathway, regulates cell differentiation in multiple tissues.
- Disruptions in the normal expression of HES5 have been associated with developmental diseases and cancer.
- HES5 is a protein coding gene.
- Diseases associated with HES5 include valproate embryopathy, susceptibility to.
- Among its related pathways are signaling by NOTCH1 and NOTCH2.
- Activation and transmission of signal to the nucleus.
- Applications:Suitable for use in Western Blot and ELISA.
- Other applications not tested.
- Recommended Dilution:Western Blot: 1:500-1:2000ELISA: 1:5000-1:20,000Optimal dilutions to be determined by the researcher.
- Storage and Stability:May be stored at 4°C for short-term only.
- Aliquot to avoid repeated freezing and thawing.
- Store at -20°C.
- Aliquots are stable for 12 months after receipt.
- For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
- Size：30ul
- Host：rabbit
- Source Antibody：human
- Grade：Affinity Purified
- Purity：Purified by immunoaffinity chromatography.
- Form：Supplied as a liquid in PBS, pH 7.4, 0.02% sodium azide, 50% glycerol.
- Specificity：Recognizes endogenous levels of human HES5. Species Crossreactivity: mouse and rat
- Isotype：IgG
- Calc Applications Abbrev：E WB
- Calc Crossreactivity：Hu Mo Rt
- Immunogen：Synthetic peptide corresponding to aa10-90 from human HES5.
- Swiss Prot Number：Q5TA89
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