SLC2A2 solute carrier family 2 member 2) is a protein coding gene.
Diseases associated with SLC2A2 include Fanconi-Bickel syndrome and diabetes mellitus, noninsulin-dependent.
Among its related pathways are type II diabetes mellitus and metabolism.
SLC2A2 encodes an integral plasma membrane glycoprotein of the liver, islet beta cells, intestine, and kidney epithelium.
The encoded protein mediates facilitated bidirectional glucose transport.
Because of its low affinity for glucose, it has been suggested as a glucose sensor.
Mutations in SLC2A2 are associated with susceptibility to diseases, including Fanconi-Bickel syndrome and noninsulin-dependent diabetes mellitus (NIDDM).
Alternative splicing results in multiple transcript variants of SLC2A2.
Applications:Suitable for use in Western Blot and ELISA.
Other applications not tested.
Recommended Dilution:Western Blot: 1:500-1:2000ELISA: 1:5000-1:20,000Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size:100ul
Host:rabbit
Source Antibody:human
Grade:Affinity Purified
Purity:Purified by immunoaffinity chromatography.
Form:Supplied as a liquid in PBS, pH 7.4, 0.02% sodium azide, 50% glycerol.
Specificity:Recognizes endogenous levels of human GTR2.
Isotype:IgG
Calc Applications Abbrev:E WB
Calc Crossreactivity:Hu
Immunogen:Synthetic peptide corresponding to aa220-300 of human GTR2.