SLC52A2 (solute carrier family 52 member 2) encodes a membrane protein which belongs to the riboflavin transporter family.
In humans, riboflavin must be obtained by intestinal absorption because it cannot be synthesized by the body.
The water-soluble vitamin riboflavin is processed to the coenzymes flavin mononucleotide (FMN) and flavin adenine dinucleotide (FAD) which then act as intermediaries in many cellular metabolic reactions.
Paralogous members of the riboflavin transporter gene family are located on chromosomes 17 and 20.
Unlike other members of this family, SLC52A2 has higher expression in brain tissue than small intestine.
Alternative splicing of this gene results in multiple transcript variants encoding the same protein.
Mutations in SLC52A2 have been associated with Brown-Vialetto-Van Laere syndrome 2--an autosomal recessive progressive neurologic disorder characterized by deafness, bulbar dysfunction, and axial and limb hypotonia.
Applications:Suitable for use in Western Blot, Immunofluorescence and ELISA.
Other applications not tested.
Recommended Dilution:Western Blot: 1:500-1:2000Immunofluorescence: 1:200-1:1000ELISA: 1:10,000Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：30ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid in PBS, 0.5% BSA, 0.02% sodium azide, 50% glycerol.
Specificity：Recognizes endogenous levels of human GPR172A.
Isotype：IgG
Calc Applications Abbrev：E IF WB
Calc Crossreactivity：Hu
Immunogen：Synthetic peptide corresponding to aa20-100 from the Internal region of human GPR172A.
