84-5477-70 [取扱停止]GPR124 100ul 536862
特徴
- ADGRA2 (Adhesion G Protein-Coupled Receptor A2) is a Protein Coding gene.
- Among its related pathways are Integrins in angiogenesis.
- GO annotations related to this gene include G-protein coupled receptor activity and transmembrane signaling receptor activity.
- An important paralog of this gene is ADGRA1.
- ndothelial receptor which functions as a WNT7-specific coactivator of canonical Wnt signaling (By similarity).
- Required for normal endothelial cell sprouting and migration in the forebrain and neural tube (By similarity).
- Has a major role in establishing the blood-brain barrier (By similarity).
- Binds to the glycosaminoglycans heparin, heparin sulfate, chondroitin sulfate and dermatan sulfate (PubMed: 16982628).
- Applications:Suitable for use in Western Blot, Immunofluorescence, and ELISA.
- Other applications not tested.
- Recommended Dilution:Western Blot: 1:500-1:2000Immunofluorescence: 1:200-1:1000ELISA: 1:10,000Optimal dilutions to be determined by the researcher.
- Storage and Stability:May be stored at 4°C for short-term only.
- Aliquot to avoid repeated freezing and thawing.
- Store at -20°C.
- Aliquots are stable for 12 months after receipt.
- For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
- Size:100ul
- Host:rabbit
- Source Antibody:human
- Grade:Affinity Purified
- Purity:Purified by immunoaffinity chromatography.
- Form:Supplied as a liquid in PBS, 0.5% BSA, 0.02% sodium azide, 50% glycerol.
- Specificity:Recognizes endogenous levels of human GPR124. Species Crossreactivity: mouse
- Isotype:IgG
- Calc Applications Abbrev:E IF WB
- Calc Crossreactivity:Hu Mo
- Immunogen:Synthetic peptide corresponding to aa1120-1200 of human GPR124 at C-terminal.
- Swiss Prot Number:Q96PE1
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