SLC2A4 is a member of the solute carrier family 2 (facilitated glucose transporter) family and encodes Solute carrier family 2 facilitated glucose transporter member 4 that functions as an insulin-regulated facilitative glucose transporter.
In the absence of insulin, solute carrier family 2 facilitated glucose transporter member 4 is sequestered within the cells of muscle and adipose tissue.
Within minutes of insulin stimulation, solute carrier family 2 facilitated glucose transporter member 4 moves to the cell surface and begins to transport glucose across the cell membrane.
Mutations in this gene have been associated with noninsulin-dependent diabetes mellitus (NIDDM).
Applications:Suitable for use in Western Blot, Immunohistochemistry, and ELISA.
Other applications not tested.
Recommended Dilution:Western Blot: 1:500-1:2000Immunohistochemistry (paraffin): 1:100-1:300ELISA: 1:40,000Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：100ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid in PBS, 0.5% BSA, 0.02% sodium azide, 50% glycerol.
Specificity：Recognizes endogenous levels of human Glut4. Species Crossreactivity: mouse, rat
Isotype：IgG
Calc Applications Abbrev：E IHC WB
Calc Crossreactivity：Hu Mo Rt
Immunogen：Synthetic peptide corresponding to the Internal region of human Glut4.
