The secretory protein encoded by GKN2 (gastrokine 2) is produced in gastric surface mucous cells, where it can bind trefoil factor family peptide 1 or gastrokine-1.
GKN2 may be a tumor suppressor gene, as its expression is markedly decreased in gastric cancer tissues.
The encoded protein interacts with gastrokine-1 and regulates homeostasis of the gastric mucosa.
GKN2 is a protein coding gene.
Diseases associated with GKN2 include gastric cancer, somatic and internuclear ophthalmoplegia.
Applications:Suitable for use in Western Blot and ELISA.
Other applications not tested.
Recommended Dilution:Western Blot: 1:500-1:2000ELISA: 1:5000-1:20,000Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：30ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid in PBS, pH 7.4, 0.02% sodium azide, 50% glycerol.
Specificity：Recognizes endogenous levels of human GKN2. Species Crossreactivity: mouse and rat
Isotype：IgG
Calc Applications Abbrev：E WB
Calc Crossreactivity：Hu Mo Rt
Immunogen：Synthetic peptide corresponding to aa30-110 of human GKN2.
