84-5473-73 ［取扱停止］GBP5 30ul 536657
特徴
- GBP5 (Guanylate Binding Protein 5) is a Protein Coding gene.
- Diseases associated with GBP5 include chronic active epstein-barr virus infection.
- Among its related pathways are Immune System and Interferon gamma signaling.
- GO annotations related to this gene include identical protein binding and GTPase activity.
- An important paralog of this gene is GBP7.
- s an activator of NLRP3 inflammasome assembly, plays a role in innate immunity and inflammation.
- Promotes selective NLRP3 inflammasome assembly in response to microbial and soluble, but not crystalline, agents (PubMed: 22461501).
- Hydrolyzes GTP, but in contrast to other family members, does not produce GMP (PubMed: 20180847).
- Applications:Suitable for use in Immunohistochemistry and ELISA.
- Other applications not tested.
- Recommended Dilution:Immunohistochemistry (paraffin): 1:100-1:300ELISA: 1:20,000Optimal dilutions to be determined by the researcher.
- Storage and Stability:May be stored at 4°C for short-term only.
- Aliquot to avoid repeated freezing and thawing.
- Store at -20°C.
- Aliquots are stable for 12 months after receipt.
- For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
- Size：30ul
- Host：rabbit
- Source Antibody：human
- Grade：Affinity Purified
- Purity：Purified by immunoaffinity chromatography.
- Form：Supplied as a liquid in PBS, 0.5% BSA, 0.02% sodium azide, 50% glycerol.
- Specificity：Recognizes endogenous levels of human GBP5.
- Isotype：IgG
- Calc Applications Abbrev：E IHC
- Calc Crossreactivity：Hu
- Immunogen：Synthetic peptide corresponding to the Internal region of human GBP5.
- Swiss Prot Number：Q96PP8
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