84-5472-69　［取扱停止］GalNAc4ST-1 100ul　536589

特徴

• The protein encoded by CHST8 (carbohydrate sulfotransferase 8) belongs to the sulfotransferase 2 family.
• It is predominantly expressed in the pituitary gland, and is localized to the golgi membrane.
• This protein catalyzes the transfer of sulfate to position 4 of non-reducing N-acetylgalactosamine (GalNAc) residues in both N-glycans and O-glycans.
• It is responsible for sulfation of GalNAc on luteinizing hormone (LH), which is required for production of the sex hormones.
• Mice lacking this enzyme, exhibit increased levels of circulating LH, and precocious sexual maturation of both male and female mice.
• Alternatively spliced transcript variants have been found for CHST8.
• Applications:Suitable for use in Western Blot and ELISA.
• Other applications not tested.
• Recommended Dilution:Western Blot: 1:500-1:2000ELISA: 1:40,000Optimal dilutions to be determined by the researcher.
• Storage and Stability:May be stored at 4°C for short-term only.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Aliquots are stable for 12 months after receipt.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.