84-5470-41　［取扱停止］Frizzled-2 30ul　536466

特徴

• FZD2 is a member of the frizzled gene family.
• Members of this family encode seven-transmembrane domain proteins that are receptors for the wingless type MMTV integration site family of signaling proteins.
• FZD2 encodes frizzled class receptor 2 that is coupled to the beta-catenin canonical signaling pathway.
• Competition between the wingless-type MMTV integration site family, member 3A and wingless-type MMTV integration site family, member 5A gene products for binding of this protein is thought to regulate the beta-catenin-dependent and -independent pathways.
• is a member of the protein-tyrosine kinase oncogene family.
• It encodes a membrane-associated tyrosine kinase that has been implicated in the control of cell growth.
• The protein associates with the p85 subunit of phosphatidylinositol 3-kinase and interacts with the fyn-binding protein.
• Alternatively spliced transcript variants encoding distinct isoforms exist.
• Applications:Suitable for use in Western Blot, Immunofluorescence, and ELISA.
• Other applications not tested.
• Recommended Dilution:Western Blot: 1:500-1:2000Immunofluorescence: 1:200-1:1000ELISA: 1:40,000Optimal dilutions to be determined by the researcher.
• Storage and Stability:May be stored at 4°C for short-term only.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Aliquots are stable for 12 months after receipt.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.