84-5467-76　［取扱停止］FIR 100ul　536332

特徴

• FARP2 is a Protein Coding gene.
• FERM RhoGEF and pleckstrin domain-containing protein 2 functions as guanine nucleotide exchange factor that activates RAC1.
• May have relatively low activity.
• Plays a role in the response to class 3 semaphorins and remodeling of the actin cytoskeleton.
• Plays a role in TNFSF11-mediated osteoclast differentiation, especially in podosome rearrangement and reorganization of the actin cytoskeleton.
• Regulates the activation of ITGB3, integrin signaling and cell adhesion.
• Diseases associated with FARP2 include verheij syndrome and aarskog-scott syndrome.
• Among its related pathways are Developmental Biology and Adherens junction.
• GO annotations related to this gene include Rho guanyl-nucleotide exchange factor activity and Rac guanyl-nucleotide exchange factor activity.
• An important paralog of this gene is FRMD3.
• Applications:Suitable for use in Western Blot, Immunofluorescence, and ELISA.
• Other applications not tested.
• Recommended Dilution:Western Blot: 1:500-1:2000Immunofluorescence: 1:200-1:1000ELISA: 1:20,000Optimal dilutions to be determined by the researcher.
• Storage and Stability:May be stored at 4°C for short-term only.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Aliquots are stable for 12 months after receipt.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.