EFEMP1 encodes a member of the fibulin family of extracellular matrix glycoproteins.
Like all members of this family, the EGF containing fibulin like extracellular matrix protein 1 contains tandemly repeated epidermal growth factor-like repeats followed by a C-terminal fibulin-type domain.
This gene is upregulated in malignant gliomas and may play a role in the aggressive nature of these tumors.
Mutations in this gene are associated with Doyne honeycomb retinal dystrophy.
Alternatively spliced transcript variants that encode the same protein have been described.
Applications:Suitable for use in Western Blot, Immunohistochemistry, and ELISA.
Other applications not tested.
Recommended Dilution:Western Blot: 1:500-1:2000Immunohistochemistry (paraffin): 1:100-1:300ELISA: 1:10,000Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：30ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid in PBS, 0.5% BSA, 0.02% sodium azide, 50% glycerol.
Specificity：Recognizes endogenous levels of human Fibulin-3. Species Crossreactivity: mouse and rat
Isotype：IgG
Calc Applications Abbrev：E IHC WB
Calc Crossreactivity：Hu Mo Rt
Immunogen：Synthetic peptide corresponding to aa80-160 of human Fibulin-3.
