84-5465-71　［取扱停止］FAM80A 30ul　536230

特徴

• RIMKLA (N-acetylaspartyl-glutamate synthetase A) is a 391aa protein that belongs to the rimK family.
• Localizing to cytoplasm, RIMKLA contains one ATP-grasp domain and binds two manganese ions per subunit.
• RIMKLA catalyzes the synthesis of N-acetylaspartyl-glutamate (NAAG).
• RIMKLA, is almost exclusively expressed in the CNS, whereas RIMKLB, which shares 65% sequence identity with RIMKLA, is expressed in CNS and testis.
• It has also been suggested that RIMKLA and RIMKLB also served to ligate free glutamate to (an) acceptor (s).
• RIMKLA catalyzed the ATP-dependent synthesis of N-acetylaspartylglutamate (NAAG) from N-acetylaspartate and L-glutamate.
• RIMKLB catalyzed this reaction as well as the synthesis of beta-citrylglutamate.
• The RIMKLA gene is conserved in chimpanzee, canine, cow and mouse, and maps to human chromosome 1p34.2.
• Applications:Suitable for use in Western Blot and ELISA.
• Other applications not tested.
• Recommended Dilution:Western Blot: 1:500-1:2000ELISA: 1:20,000Optimal dilutions to be determined by the researcher.
• Storage and Stability:May be stored at 4°C for short-term only.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Aliquots are stable for 12 months after receipt.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.