EYA1 encodes a member of the eyes absent (EYA) family of proteins.
The encoded protein may play a role in the developing kidney, branchial arches, eye, and ear.
Mutations of EYA1 have been associated with branchiootorenal dysplasia syndrome, branchiootic syndrome, and sporadic cases of congenital cataracts and ocular anterior segment anomalies.
A similar protein in mice can act as a transcriptional activator.
Alternatively spliced transcript variants have been identified for this gene EYA1 (EYA Transcriptional Coactivator And Phosphatase 1) is a Protein Coding gene.
Diseases associated with EYA1 include Otofaciocervical Syndrome and Branchiootic Syndrome 1.
Among its related pathways are DNA Double Strand Break Response and DNA Double-Strand Break Repair.
Applications:Suitable for use in Immunohistochemistry, ELISA.
Other applications not tested.
Recommended Dilution:Immunohistochemistry (paraffin): 1:50-1:200ELISA: 1:10,000-1:20,000Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：100ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid in PBS, pH 7.4, 0.02% sodium azide, 50% glycerol.
Specificity：Recognizes endogenous levels of human EYA1/EYA4 . Species Crossreactivity: Mouse
Isotype：IgG
Calc Applications Abbrev：E IHC
Calc Crossreactivity：Hu Mo
Immunogen：Synthetic peptide corresponding to aa271-320 of human EYA1/EYA4.
