84-5458-69 [取扱停止]EGFR, phosphorylated (Tyr1069) 30ul 535864
特徴
- The epidermal growth factor receptor encoded by EGFR is a transmembrane glycoprotein that is a member of the protein kinase superfamily.
- This protein is a receptor for members of the epidermal growth factor family.
- EGFR is a cell surface protein that binds to epidermal growth factor.
- Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation.
- Mutations in this gene are associated with lung cancer.
- Applications:Suitable for use in Western Blot and ELISA.
- Other applications not tested.
- Recommended Dilution:Western Blot: 1:500-1:2000ELISA: 1:20,000Optimal dilutions to be determined by the researcher.
- Storage and Stability:May be stored at 4°C for short-term only.
- Aliquot to avoid repeated freezing and thawing.
- Store at -20°C.
- Aliquots are stable for 12 months after receipt.
- For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
- Size:30ul
- Host:rabbit
- Source Antibody:human
- Grade:Affinity Purified
- Purity:Purified by immunoaffinity chromatography.
- Form:Supplied as a liquid in PBS, 0.5% BSA, 0.02% sodium azide, 50% glycerol.
- Specificity:Recognizes endogenous levels of human EGFR (phospho Tyr1069). Species Crossreactivity: mouse, rat, and monkey
- Isotype:IgG
- Calc Applications Abbrev:E WB
- Calc Crossreactivity:Hu Mk Mo Rt
- Immunogen:Synthetic peptide corresponding to human EGFR around the phosphorylation site of Y1069.
- Swiss Prot Number:P00533
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