DUSP14 (dual specificity phosphatase 14) is a protein coding gene.
Diseases associated with DUSP14 include chromosome 17Q12 deletion syndrome.
Among its related pathways are TGF-beta pathway and hypertrophy model.
Dual-specificity phosphatases (DUSPs) constitute a large heterogeneous subgroup of the type I cysteine-based protein-tyrosine phosphatase superfamily.
DUSPs are characterized by their ability to dephosphorylate both tyrosine and serine/threonine residues.
They have been implicated as major modulators of critical signaling pathways.
DUSP14 contains the consensus DUSP C-terminal catalytic domain but lacks the N-terminal CH2 domain found in the MKP (mitogen-activated protein kinase phosphatase) class.
Applications:Suitable for use in Western Blot and ELISA.
Other applications not tested.
Recommended Dilution:Westrern Blot: 1:500-1:2000ELISA: 1:5000-1:20,000Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size:100ul
Host:rabbit
Source Antibody:human
Grade:Affinity Purified
Purity:Purified by immunoaffinity chromatography.
Form:Supplied as a liquid in PBS, pH 7.4, 0.02% sodium azide, 50% glycerol.
Specificity:Recognizes endogenous levels of human DUS14. Species Crossreactivity: mouse
Isotype:IgG
Calc Applications Abbrev:E WB
Calc Crossreactivity:Hu Mo
Immunogen:Synthetic peptide corresponding to aa120-200 of human DUS14.