84-5455-64　［取扱停止］Dsg1 30ul　535701

特徴

• DSG1 encodes a member of the desmoglein protein subfamily.
• Desmogleins, along with desmocollins, are cadherin-like transmembrane glycoproteins that are major components of the desmosome.
• Desmosomes are cell-cell junctions that help resist shearing forces and are found in high concentrations in cells subject to mechanical stress.
• DSG1 is found in a cluster with other desmoglein family members on chromosome 18.
• The desmoglein 1 has been identified as a target of auto-antibodies in the autoimmune skin blistering disease pemphigus foliaceus.
• Disruption of this gene has also been associated with the skin diseases palmoplantar keratoderma and erythroderma.
• Applications:Suitable for use in Western Blot and ELISA.
• Other applications not tested.
• Recommended Dilution:Western Blot: 1:500-1:2000ELISA: 1:40,000Optimal dilutions to be determined by the researcher.
• Storage and Stability:May be stored at 4°C for short-term only.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Aliquots are stable for 12 months after receipt.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.