DSCAM is a member of the immunoglobulin superfamily of cell adhesion molecules (Ig-CAMs) and is involved in human central and peripheral nervous system development.
DSCAM is a candidate for Down syndrome and congenital heart disease (DSCHD).
A gene encoding a similar Ig-CAM protein is located on chromosome 11.
Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
DSCAM (DS cell adhesion molecule) is a protein coding gene.
Diseases associated with DSCAM include Down Syndrome-related congenital heart disease and Down syndrome.
Among its related pathways are cell junction organization and guidance cues and growth cone motility.
An important paralog of this gene is DSCAML1.
Applications:Suitable for use in Western Blot and ELISA.
Other applications not tested.
Recommended Dilution:Western Blot: 1:500-1:2000ELISA: 1:5000-1:20,000Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：100ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid in PBS, pH 7.4, 0.02% sodium azide, 50% glycerol.
Specificity：Recognizes endogenous levels of human DSCAM. Species Crossreactivity: mouse and rat
Isotype：IgG
Calc Applications Abbrev：E WB
Calc Crossreactivity：Hu Mo Rt
Immunogen：Synthetic peptide corresponding to human DSCAM protein.
