84-5454-89 ［取扱停止］DOT1L 30ul 535664
特徴
- DOT1L encoded by this gene is a histone methyltransferase that methylates lysine-79 of histone H3.
- It is inactive against free core histones, but shows significant histone methyltransferase activity against nucleosomes.
- DOT1L (DOT1 like histone lysine methyltransferase) is a protein coding gene.
- Diseases associated with DOT1L include diffuse gastric cancer and leukemia, acute myeloid.
- Among its related pathways are chromatin organization and transcriptional misregulation in cancer.
- Applications:Suitable for use in Western Blot and ELISA.
- Other applications not tested.
- Recommended Dilution:Western Blot: 1:500-1:2000ELISA: 1:5000-1:20,000Optimal dilutions to be determined by the researcher.
- Storage and Stability:May be stored at 4°C for short-term only.
- Aliquot to avoid repeated freezing and thawing.
- Store at -20°C.
- Aliquots are stable for 12 months after receipt.
- For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
- Size：30ul
- Host：rabbit
- Source Antibody：human
- Grade：Affinity Purified
- Purity：Purified by immunoaffinity chromatography.
- Form：Supplied as a liquid in PBS, pH 7.4, 0.02% sodium azide, 50% glycerol.
- Specificity：Recognizes endogenous levels of human DOT1L.
- Isotype：IgG
- Calc Applications Abbrev：E WB
- Calc Crossreactivity：Hu
- Immunogen：Synthetic peptide corresponding to aa700-780 of human DOT1L.
- Swiss Prot Number：Q8TEK3
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