84-5454-16　［取扱停止］DnaJC17 30ul　535627

特徴

• The DnaJ family is one of the largest of all chaperone families and has evolved with diverse cellular localization and functions.
• The presence of the J domain defines a protein as a member of the DnaJ family.
• DnaJ heat shock induced proteins are from the bacterium Escherichia coli and are under the control of the htpR regulatory protein.
• The DnaJ proteins play a critical role in the HSP 70 chaperone machine by interacting with HSP 70 to stimulate ATP hydrolysis.
• The proteins contain cysteine rich regions that are composed of zinc fingers, forming peptide binding domains responsible for chaperone function.
• DnaJ proteins are important mediators of proteolysis and are involved in the regulation of protein degradation, exocytosis and endocytosis.
• DNAJC17 (DnaJ (Hsp40) homolog, subfamily C, member 17) is a 304aa protein containing a J domain and a RRM (RNA recognition motif) domain.
• Applications:Suitable for use in Western Blot and ELISA.
• Other applications not tested.
• Recommended Dilution:Western Blot: 1:500-1:2000ELISA: 1:20,000Optimal dilutions to be determined by the researcher.
• Storage and Stability:May be stored at 4°C for short-term only.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Aliquots are stable for 12 months after receipt.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.