DLG3 (discs large MAGUK scaffold protein 3) is a protein coding gene.
Diseases associated with DLG3 include X-linked non-specific intellectual disability and non-syndromic intellectual disability.
Among its related pathways are PI3K-Akt signaling pathway and protein-protein interactions at synapses.
DLG3 encodes a member of the membrane-associated guanylate kinase protein family.
The encoded protein may play a role in clustering of NMDA receptors at excitatory synapses.
It may also negatively regulate cell proliferation through interaction with the C-terminal region of the adenomatosis polyposis coli tumor suppressor protein.
Mutations in this gene have been associated with X-linked cognitive disability.
Alternatively spliced transcript variants have been described.
Applications:Suitable for use in Western Blot and ELISA.
Other applications not tested.
Recommended Dilution:Western Blot: 1:500-1:2000ELISA: 1:5000-1:20,000Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：30ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid in PBS, pH 7.4, 0.02% sodium azide, 50% glycerol.
Specificity：Recognizes endogenous levels of human DLG3. Species Crossreactivity: mouse and rat
Isotype：IgG
Calc Applications Abbrev：E WB
Calc Crossreactivity：Hu Mo Rt
Immunogen：Synthetic peptide corresponding to human DLG3 protein.
