The cysteinyl leukotrienes LTC4, LTD4, and LTE4 are important mediators of human bronchial asthma.
Pharmacologic studies have determined that cysteinyl leukotrienes activate at least 2 receptors, the protein encoded by CYSLTR2 (cysteinyl leukotriene receptor 2)and CYSLTR1.
This encoded receptor is a member of the superfamily of G protein-coupled receptors.
It seems to play a major role in endocrine and cardiovascular systems.
Applications:Suitable for use in Western Blot, Immunofluorescence, and ELISA.
Other applications not tested.
Recommended Dilution:Western Blot: 1:500-1:2000Immunofluorescence: 1:200-1:1000ELISA: 1:20,000Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：100ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid in PBS, 0.5% BSA, 0.02% sodium azide, 50% glycerol.
Specificity：Recognizes endogenous levels of human CysLTR2.
Isotype：IgG
Calc Applications Abbrev：E IF WB
Calc Crossreactivity：Hu
Immunogen：Synthetic peptide corresponding to aa260-340 of human CysLTR2 at C-terminal.
