84-5447-60　［取扱停止］CYFP1 30ul　535278

特徴

• CYFIP1 (cytoplasmic FMR1 interacting protein 1) encodes a protein that regulates cytoskeletal dynamics and protein translation.
• The encoded protein is a component of the WAVE regulatory complex (WRC), which promotes actin polymerization.
• This protein also interacts with the fragile X mental retardation protein (FMRP) and translation initiation factor 4E to inhibit protein translation.
• A large chromosomal deletion including CYFIP1 is associated with increased risk of schizophrenia and epilepsy in human patients.
• Reduced expression of CYFIP1 has been observed in various human cancers and the encoded protein may inhibit tumor invasion.
• CYFIP1 is a protein coding gene.
• Diseases associated with CYFIP1 include fragile X syndrome and schizophrenia.
• Among its related pathways are RET signaling and regulation of actin dynamics for phagocytic cup formation.
• Applications:Suitable for use in Western Blot and ELISA.
• Other applications not tested.
• Recommended Dilution:Western Blot: 1:500-1:2000ELISA: 1:5000-1:20,000Optimal dilutions to be determined by the researcher.
• Storage and Stability:May be stored at 4°C for short-term only.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Aliquots are stable for 12 months after receipt.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.