Fractalkine is a transmembrane protein and chemokine involved in the adhesion and migration of leukocytes.
CX3C chemokine receptor 1 encoded by CX3CR1 is a receptor for fractalkine.
The encoded protein also is a coreceptor for HIV-1, and some variations in CX3CR1 lead to increased susceptibility to HIV-1 infection and rapid progression to AIDS.
Four transcript variants encoding two different isoforms have been found for this gene.
Applications:Suitable for use in Immunohistochemistry, Immunofluorescence, and ELISA.
Other applications not tested.
Recommended Dilution:Immunohistochemistry (paraffin): 1:100-1:300Immunofluorescence: 1:200-1:1000ELISA: 1:5000Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：100ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid in PBS, 0.5% BSA, 0.02% sodium azide, 50% glycerol.
Specificity：Recognizes endogenous levels of human CX3CR1.
Isotype：IgG
Calc Applications Abbrev：E IF IHC
Calc Crossreactivity：Hu
Immunogen：Synthetic peptide corresponding to aa270-350 of human CX3CR1 at C-terminal.
