84-5446-49 ［取扱停止］CUL7 30ul 535206
特徴
- The protein encoded by CUL7 (Cullin 7) is a component of an E3 ubiquitin-protein ligase complex.
- The encoded protein interacts with TP53, CUL9, and FBXW8 proteins.
- Defects in CUL7 are a cause of 3M syndrome type 1 (3M1).
- Two transcript variants encoding different isoforms have been found for CUL7.
- CUL7 is a protein coding gene.
- Diseases associated with CUL7 include 3-M syndrome 1 and 3-M syndrome, Cul7-related.
- Among its related pathways are class I MHC mediated antigen processing and presentation and unfolded protein response (UPR).
- Applications:Suitable for use in Western Blot and ELISA.
- Other applications not tested.
- Recommended Dilution:Western Blot: 1:500-1:2000ELISA: 1:5000-1:20,000Optimal dilutions to be determined by the researcher.
- Storage and Stability:May be stored at 4°C for short-term only.
- Aliquot to avoid repeated freezing and thawing.
- Store at -20°C.
- Aliquots are stable for 12 months after receipt.
- For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
- Size：30ul
- Host：rabbit
- Source Antibody：human
- Grade：Affinity Purified
- Purity：Purified by immunoaffinity chromatography.
- Form：Supplied as a liquid in PBS, pH 7.4, 0.02% sodium azide, 50% glycerol.
- Specificity：Recognizes endogenous levels of human CUL7. Species Crossreactivity: mouse
- Isotype：IgG
- Calc Applications Abbrev：E WB
- Calc Crossreactivity：Hu Mo
- Immunogen：Synthetic peptide corresponding to aa1570-1650 of human CUL7.
- Swiss Prot Number：Q14999
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