The adenovirus E1A protein both activates and represses gene expression to promote cellular proliferation and inhibit differentiation.
The protein encoded by this gene antagonizes transcriptional activation and cellular transformation by E1A.
Cellular repressor of E1A stimulated genes 1 shares limited sequence similarity with E1A and binds both the general transcription factor TBP and the tumor suppressor pRb in vitro.
CREG1 may contribute to the transcriptional control of cell growth and differentiation.
CREG1 (cellular repressor of E1A stimulated genes 1) is a protein coding gene.
Among its related pathways are nnate immune system and senescence and autophagy in cancer.
Applications:Suitable for use in Western Blot and ELISA.
Other applications not tested.
Recommended Dilution:Western Blot: 1:500-1:2000ELISA: 1:5000-1:20,000Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：30ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid in PBS, pH 7.4, 0.02% sodium azide, 50% glycerol.
Specificity：Recognizes endogenous levels of human CREG1.
Isotype：IgG
Calc Applications Abbrev：E WB
Calc Crossreactivity：Hu
Immunogen：Synthetic peptide corresponding to human CREG1 protein.
