CPA1 encodes a member of the carboxypeptidase A family of zinc metalloproteases.
This enzyme (carboxypeptidase A1) is produced in the pancreas and preferentially cleaves C-terminal branched-chain and aromatic amino acids from dietary proteins.
This gene and several family members are present in a gene cluster on chromosome 7.
Mutations in CPA1 may be linked to chronic pancreatitis, while elevated protein levels may be associated with pancreatic cancer.
Applications:Suitable for use in Western Blot, Immunohistochemistry, and ELISA.
Other applications not tested.
Recommended Dilution:Western Blot: 1:500-1:2000Immunohistochemistry (paraffin): 1:100-1:300ELISA: 1:40,000Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size:30ul
Host:rabbit
Source Antibody:human
Grade:Affinity Purified
Purity:Purified by immunoaffinity chromatography.
Form:Supplied as a liquid in PBS, 0.5% BSA, 0.02% sodium azide, 50% glycerol.
Specificity:Recognizes endogenous levels of human CPA1.
Isotype:IgG
Calc Applications Abbrev:E IHC WB
Calc Crossreactivity:Hu
Immunogen:Synthetic peptide corresponding to aa270-350 of human CPA1.