CYP3A5 (cytochrome P450 family 3 subfamily A member 5) is a protein coding gene.
Diseases associated with CYP3A5 include hypertension, essential and Cyp3a5-related altered drug metabolism.
Among its related pathways are Imipramine/Desipramine pathway, pharmacokinetics and metabolism.
CYP3A5 encodes a member of the cytochrome P450 superfamily of enzymes.
The encoded protein metabolizes drugs as well as the steroid hormones testosterone and progesterone.
CYP3A5 is part of a cluster of cytochrome P450 genes on chromosome 7q21.1.
Expression of this gene is widely variable among populations, and a single nucleotide polymorphism that affects transcript splicing has been associated with susceptibility to hypertensions.
Alternative splicing results in multiple transcript variants.
Applications:Suitable for use in Western Blot and ELISA.
Other applications not tested.
Recommended Dilution:Western Blot: 1:500-1:2000ELISA: 1:5000-1:20,000Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：30ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid in PBS, pH 7.4, 0.02% sodium azide, 50% glycerol.
Specificity：Recognizes endogenous levels of human CP3A5.
Isotype：IgG
Calc Applications Abbrev：E WB
Calc Crossreactivity：Hu
Immunogen：Synthetic peptide corresponding to aa200-280 of human CP3A5.
