Complement component C3 plays a central role in the activation of complement system.
Its activation is required for both classical and alternative complement activation pathways.
Complement C3 is proteolytically processed to generate alpha and beta subunits that form the mature protein, which is then further processed to generate numerous peptide products.
The C3a peptide, also known as the C3a anaphylatoxin, modulates inflammation and possesses antimicrobial activity.
Mutations in C3 are associated with atypical hemolytic uremic syndrome and age-related macular degeneration in human patients.
Applications:Suitable for use in Western Blot and ELISA.
Other applications not tested.
Recommended Dilution:Western Blot: 1:500-1:2000ELISA: 1:5000-1:20,000Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：100ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid in PBS, pH 7.4, 0.02% sodium azide, 50% glycerol.
Specificity：Recognizes endogenous levels of human CO3. Species Crossreactivity: Mouse, Rat
Isotype：IgG
Calc Applications Abbrev：E WB
Calc Crossreactivity：Hu Mo Rt
Immunogen：Synthetic peptide corresponding to human CO3 protein.
