CLCNKA is a member of the CLC family of voltage-gated chloride channels.
The encoded protein (chloride voltage-gated channel Ka) is predicted to have 12 transmembrane domains, and requires a beta subunit called barttin to form a functional channel.
It is thought to function in salt reabsorption in the kidney and potassium recycling in the inner ear.
The gene is highly similar to CLCNKB, which is located 10kb downstream from this gene.
Multiple transcript variants encoding different isoforms have been found for CLCNKA.
Applications:Suitable for use in Western Blot and ELISA.
Other applications not tested.
Recommended Dilution:Western Blot: 1:500-1:2000ELISA: 1:40,000Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：100ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid in PBS, 0.5% BSA, 0.02% sodium azide, 50% glycerol.
Specificity：Recognizes endogenous levels of human CLC-KA.
Isotype：IgG
Calc Applications Abbrev：E WB
Calc Crossreactivity：Hu
Immunogen：Synthetic peptide corresponding to aa550-630 of human CLC-KA at C-terminal.
