84-5438-22　［取扱停止］CLAP2 30ul　534762

特徴

• CLASP2 (cytoplasmic linker associated protein 2) is a protein coding gene.
• Diseases associated with CLASP2 include clostridium difficile colitis.
• Among its related pathways are DNA damage and cell cycle, mitotic.
• microtubule plus-end tracking protein that promotes the stabilization of dynamic microtubules.
• Involved in the nucleation of noncentrosomal microtubules originating from the trans-golgi network (TGN).
• Required for the polarization of the cytoplasmic microtubule arrays in migrating cells towards the leading edge of the cell.
• This cortical microtubule stabilizing activity is regulated at least in part by phosphatidylinositol 3-kinase signaling.
• Also performs a similar stabilizing function at the kinetochore which is essential for the bipolar alignment of chromosomes on the mitotic spindle.
• Acts as a mediator of ERBB2-dependent stabilization of microtubules at the cell cortex.
• Applications:Suitable for use in Western Blot and ELISA.
• Other applications not tested.
• Recommended Dilution:Western Blot: 1:500-1:2000ELISA: 1:5000-1:20,000Optimal dilutions to be determined by the researcher.
• Storage and Stability:May be stored at 4°C for short-term only.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Aliquots are stable for 12 months after receipt.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.