CIDEC (cell death inducing DFFA like effector c) encodes a member of the cell death-inducing DNA fragmentation factor-like effector family.
Members of this family play important roles in apoptosis.
The encoded protein promotes lipid droplet formation in adipocytes and may mediate adipocyte apoptosis.
CIDEC is regulated by insulin and its expression is positively correlated with insulin sensitivity.
Mutations in CIDEC may contribute to insulin resistant diabetes.
A pseudogene of CIDEC is located on the short arm of chromosome 3.
Alternatively spliced transcript variants that encode different isoforms have been observed for CIDEC.
Applications:Suitable for use in Immunohistochemistry, Immunofluorescence, ELISA.
Other applications not tested.
Recommended Dilution:Immunohistochemistry (paraffin): 1:100-1:300Immunofluorescence: 1:200-1:1000ELISA: 1:5000Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：30ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid in PBS, 0.5% BSA, 0.02% sodium azide, 50% glycerol.
Specificity：Recognizes endogenous levels of human CIDE-3.
Isotype：IgG
Calc Applications Abbrev：E IF IHC
Calc Crossreactivity：Hu
Immunogen：Synthetic peptide corresponding to aa160-240 from human CIDE-3 at C-terminal.
