CHD6 (chromodomain helicase DNA binding protein 6) is a protein coding gene.
Diseases associated with CHD6 include Pitt-Hopkins syndrome and developmental coordination disorder.
CHD6 encodes a member of the SNF2/RAD54 helicase protein family.
The encoded protein contains two chromodomains, a helicase domain, and an ATPase domain.
Several multi-subunit protein complexes remodel chromatin to allow patterns of cell type-specific gene expression, and the encoded protein is thought to be a core member of one or more of these chromatin remodeling complexes.
The encoded protein may function as a transcriptional repressor and is involved in the cellular repression of influenza virus replication.
Applications:Suitable for use in Immunohistochemistry (paraffin).
Other applications not tested.
Recommended Dilution:Immunohistochemistry (paraffin): 1:50-1:300Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size:30ul
Host:rabbit
Source Antibody:human
Grade:Affinity Purified
Purity:Purified by immunoaffinity chromatography.
Form:Supplied as a liquid in PBS, pH 7.4, 0.02% sodium azide, 50% glycerol.
Specificity:Recognizes endogenous levels of human CHD6.
Isotype:IgG
Calc Applications Abbrev:IHC
Calc Crossreactivity:Hu
Immunogen:Synthetic peptide corresponding to human CHD6 protein.