CDK19 (cyclin dependent kinase 19) encodes a protein that is one of the components of the mediator co-activator complex.
The mediator complex is a multi-protein complex required for transcriptional activation by DNA binding transcription factors of genes transcribed by RNA polymerase II.
The protein encoded by CDK19 is similar to cyclin-dependent kinase 8 which can also be a component of the mediator complex.
Alternative splicing results in multiple transcript variants encoding distinct isoforms.
CDK19 is a protein coding gene.
Among its related pathways are metabolism and regulation of lipid metabolism by peroxisome proliferator-activated receptor alpha (PPARalpha).
Applications:Suitable for use in Western Blot and ELISA.
Other applications not tested.
Recommended Dilution:Western Blot: 1:500-1:2000ELISA: 1:5000-1:20,000Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：100ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid in PBS, pH 7.4, 0.02% sodium azide, 50% glycerol.
Specificity：Recognizes endogenous levels of human CDK19. Species Crossreactivity: mouse
Isotype：IgG
Calc Applications Abbrev：E WB
Calc Crossreactivity：Hu Mo
Immunogen：Synthetic peptide corresponding to aa30-110 from human CDK19.
